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Fernando Constantino-Casas

Fernand Constantino Casas Pathologist


RCVS Recognised Specialist in Veterinary Anatomic Pathology

Professional history

Fernando Constantino-Casas graduated with a Bachelor degree in Veterinary Medicine from the National Autonomus University of Mexico in 1985. He was awarded a PhD degree from the University of Cambridge in 1991. Fernando was head of the department of Pathology at the veterinary school in Mexico City from 2001 to 2006. He was then was appointed as Senior Lecturer in veterinary pathology, University of Cambridge in 2007 and as University Pathologist in March 2014. He has published 52 papers in peer review journals. He has supervised 14 undergraduate thesis, 8 Master thesis and 5 PhD thesis.

Special interests

Veterinary oncology.
Hepatitis and pancreatitis in dogs and cats.
Infectious diseases.
Syringomyelia in Cavalier King Charles Spaniels.
Pain assessment in sheep.
Please visit Fernando’s research profile for further information.

Recent publications

Erich Suzzanne A., Constantino-Casas F, Dobson JM & Teske E. Morphological distinction of histocytic sarcoma from other tumor types in Bernese Mountain Dogs and Flat coated retrievers. In Vivo. In press 2017.

Giuliano A, Dos Santos Horta R, Constantino-Casas F, Hoather T, and Dobson JM. Expression of Fibroblast Activating Protein and Correlation with Histological Grade, Mitotic Index and Ki67 Expression in Canine Mast Cell tumours. J Comp Path. 2017;156(1), 14-20.

Garcia LJ, Gonzalez DG, Prado OM, Macedo JR, Ramirez R, Martinez J, Barrios HB. Lopez A, Constantino F.  Identification of non-tuberculous mycobacteria isolated from opossum (Didelphis virginiana) lymph nodes and charactierisation of lesions. Australian Journal of Veterinary Science, 2017;49, 199-203.

Hughes K, Constantino-Casas F, Haverson V, Philp S. Pathology in practice: Yersinia pseudotuberculosis infection in three captive Egyptian fruit bats (Rousettus aegyptiacus). Journal of the American Veterinary Medical Association. In press 2016.

McLennan KM, Corke MJ, Rebelo C, Broom D, Constantino-Casas F. Development of a facial expression scale using footrot and mastitis as models of pain in sheep. Applied Animal Behaviour Science, 2016;176, 19-26.

Kent ACC, Constantino-Casas F, Rusbridge C, Corcoran BM, Carter M, Leadger T, Watson PJ. Prevalence of pancreatic, hepatic and renal microscopic lesions in post-mortem samples from cavalier King Charles spaniels. Journal of Small Animal Practice, 2016;57, 188-193.

Dobson JM, Hoather T, Constantino-Casas F. Flat-Coated Retriever dog tumour survey 25 years. Veterinary Times;2016;11, 14-18.

Giuliano A, Swift R, Arthurs A, Marote G, Abramo F, McKay J, Thomson C, Beltran M, Millar M, Priestnall S, Dobson JM, Constantino-Casas F, Petrou T, McGonnell IM, Davies AJ, Weetman M, Garden OA, Masters JR, Thrasivoulou C, Ahmed A. Quantitative Expression and Co-localization of Wnt signalling related proteins in Feline Squamous cell carcinoma. PLoS ONE;2016;25, 1-17.

Kent A, Constantino-Casas F, Herrtage ME. Naturally occuring acquired primary hypothyroidism in a cat due to lymphocytic thyroiditis. Veterinary Record Case Reports, 2016;4(1), doi:10.1136/vetreccr- 2015-000282

Hughes K, Archer J, Constantino-Casas F, Wozniakowski G, Baigent S. Diagnostic Investigation of Marek’s disease in a turkey. Veterinary Record Case Reports. 2016;4(1),  doi:10.1136/ vetreccr-2016-000291.

Rad R, Rad L, Wang W, Strong A, Ponstingl A, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Ollinger R, Zukowska M, Barenboim M, Maresch R, Caldinanos J, Friedrich M, Varela I, Constantino-Casas F, Sarver A, ten Hoeve J, Prosser H, et al. A conditional PiggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer. Nature Genetics, 2015;47(1), 47-56.

Salgüero R, Demetriou J, Constantino-Casas F, Herrtage M. Hypertrophic Osteopathy in a cat with a concurrent injection site sarcoma. Journal of Feline Medicine and Surgery, Open reports, 2015; DOI:10.1177/2055116915593968

McLennan KM, Skillings EA, Rebelo CJB, Corke MJ, Pires Moreira MA, Morton AJ, Constantino-Casas F. Technical validation of an automatic recording system to assess behavioural activity level in sheep (Ovis aries). Small Ruminant Research, 2015;127, 92-96.

Marcinowska A, Constantino-Casas F, Dobson JM. Histiocytic sarcoma in a flat coated retriever with central and peripheral nervous system sarcomatosis. Veterinary Record Case Reports 2014;2 e000029. DOI: 10.1136/vetreccr-2013-000029.

Rupp A, Ives E, Rudorf H, Constantino-Casas F. Sciatic T-cell neurolymphomatosis in a dog. Veterinary Record Case Reports, 2014; 2 e000050. doi:10.1136/vetreccr-2014-000050

Rad R, Strong A, Varela I, Kriegl L, Fraga MF, Calvanese V, Saur D, Price S, McDermott U, Eser S, Constantin-Casas F, Kirchner T, Yusa K, Grove C, Seidler B, Schmid RM. A genetic progression model of BrafV600E-induced intestinal tumourigenesis reveals targets for therapeutic intervention. Cancer Cell, 2013;24, 1-15.

Furtado ARR, Constantino-Casas F. Histopathology inflammation scoring and classification in 34 dogs with inflammatory nasal disease. Veterinary Record, 2013;173(3), 71.

Harris BJ, Constantino-Casas F, Archer J, Herrtage ME. Loeffler’s Endocarditis and Bicavity Eosinophilic Effusios in a Dog with Vesceral Mas Cell Tumour and Hypereosinophilia. Journal of Comparative Pathology, 2013;149(4), 429-33.

Abbondati E, Del-Pozo J, Hoather TH, Constantino-Casas F, Dobson JM. An Immunohistochemical Study of the Expression of the Hypoxia Markers Glut-1 and Ca-IX in Canine Sarcomas. Veterinary Pathology, 2013;50(6), 1063-1069.

Bexfield NH, Buxton RJ, Vicek TJ, Day MJ, Bailey SM, Haugland SP, Morrison LR, Else RW, Constantino-Casas F, Watson PJ. Breed, age and gender distribution of dogs with chronic hepatitis in the United Kingdom. The Veterinary Journal, 2012;193, 124-128.

Demetriou JL, Brearley MJ, Constantino-Casas F, Addington CE and Dobson JM. Intentional marginal excision of canine limb soft tissue sarcomas followed by radiotherapy. Journal of Small Animal Practice, 2012;53, 174-181.

Vanhaesebrouck AE, Posch B, Baker S, Plessas IN, Palmer AC, Constantino-Casas F. Temporal lobe epilepsy in a cat with a pyriform lobe oligodendroglioma and hippocampal necrosis. Journal of Feline Medicine and Surgery, 2012;14, 932-937.

Hu HZ, Rusbridge C, Constantino-Casas F, Jeffery N. Distribution of substance P and calcitonin gene-related peptide in the spinal cord of Cavalier King Charles Spaniels affected by symptomatic syringomyelia. Research in Veterinary Science, 2012;93, 318-320.

Hu HZ, Rusbridge C, Constantino-Casas F, Jeffery N. Histopathological Investigation of Syringomyelia in the Cavalier King Charles Spaniel. Journal of Comparative Pathology, 2012;146, 192-194.