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Tim Williams

Tim Williams Clinical PathologyMA VetMB PhD FRCPath DipECVCP MRCVS

Lecturer in Clinical Pathology

Professional history
Tim qualified from the University of Cambridge in 2007, and following a year working in small animal practice in west London, he undertook a PhD in the Feline Research Group at the Royal Veterinary College, London under the supervision of Professor Jonathan Elliott and Professor Harriet Syme. His research focused on feline geriatric medicine and, in particular, the effect of hyperthyroidism on renal function in cats. He received the Society for Comparative Endocrinology award for “Excellence in the Advancement in Veterinary Endocrinology” in 2011 and 2015. Tim joined the department in 2012 as Senior Clinical Training Scholar in Veterinary Clinical Pathology and subsequently became Lecturer in Clinical Pathology in September 2015. He is a Fellow of the Royal College of Pathologists and a Diplomate of the European College of Veterinary Clinical Pathology.

Special interests

See Tim's research profile for more information

Urinary exosomes, endocrinology and nephrology particularly hyperthyroidism, hypertension and chronic kidney disease in cats; Disorders of calcium and phosphate homeostasis; Prognostic value of flow cytometry

Recent publications

Kortum AJ, Cloup EA, Williams TL, Constantino-Casas F, Watson PJ. An investigation into hepatocyte expression and prognostic significance of senescence marker p21 in canine chronic hepatitis. Journal of Veterinary Internal Medicine. (2018) 32(5): 1629-1636.

McCallum KE, Stubbs S, Hope N, Mickleburgh I, Dight D, Tiley L, Williams TL. Detection of morbillivirus and other paramyxoviruses in urine samples of cats with and without chronic kidney disease (CKD) in the United Kingdom. Journal of Veterinary Internal Medicine. (2018) 32(3): 1000-1008.

van den Broek DHN, Geddes RF, Williams TL, Chang YM, Elliott J and Jepson RE. Calcitonin response to naturally occurring ionized hypercalcemia in cats with chronic kidney disease. Journal of Veterinary Internal Medicine. (2018) 32(2): 727-735. 

Goodband E, Serrano G, Constantino-Casas F, Archer J, Watson PJ*, Williams TL*. Technical and biological validation of a 1,2-O-Dilauryl-Rac-Glycero Glutaric Acid-(6’-methylresorufin) ester (DGGR) lipase assay for use in canine serum. Veterinary Record Open. (2018) 5: e000270.

Sanchini L, Reading M, Williams TL, Archer J. Unusual clinical presentation of cryptococcosis in an immunocompetent cat. Veterinary Record Case Reports. (2017) e000524.

Williams TL, Elliott J, Syme HM, Archer J. Investigation of the association between serum protein concentrations and concurrent chronic kidney disease in hyperthyroid cats. Research in Veterinary Science. (2017) 115: 412-417.

Marcinowska A, Constantino-Casas F, Williams TL, Hoather T, Blacklaws B, Dobson J. T lymphocytes in histiocytic sarcomas of Flat-coated retrievers - a retrospective study. Veterinary Pathology. (2017) 54(4): 605-610.

Gracia T, Wang X, Su Y, Norgett E, Williams TL, Moreno P, Micklem G, Karet Frankl FE. Urinary exosomes contain microRNAs capable of paracrine modulation of tubular transporters in kidney. Scientific Reports. (2017) 7: 40601.

Williams TL, Dillon H, Syme HM, Elliott J, Archer J. Serum cystatin C concentrations in cats with hyperthyroidism and chronic kidney disease. Journal of Veterinary Internal Medicine (2016) 30(4): 1083-1089.

Williams TL, Archer J. Effect of pre-warming EDTA blood samples to 37oC on platelet count measured by Sysmex XT-2000iV in dogs, cats and horses. Veterinary Clinical Pathology (2016) 45(3): 444-449.

Williams TL, Archer J. Evaluation of urinary biomarkers for azotaemic chronic kidney disease in cats. Journal of Small Animal Practice. (2016) 27: 122-127.

Williams TL, Archer J. Validation of an automated enzyme immunoassay for the measurement of serum total thyroxine in cats. Veterinary Clinical Pathology. (2016) 45(1): 148-153.

Pitorri F, Carmichael N, Massei G, Coats J, Cowan D, Brash M, Williams TL. Comparison of serum biochemistry and haematology values in captive and free-ranging wild boar (Sus scrofa). Comparative Clinical Pathology (2015) 24(2): 281-286.

Ives EJ, Doyle L, Holmes M, Williams TL, Vanhaesebrouck AE. Association between the identification of a syrinx in asymptomatic Cavalier King Charles Spaniels and the subsequent development of clinical syringomyelia. The Veterinary Journal (2015) 203(1): 129-130.

Sommerey CC, Williams TL, McCrone I, Ruiz-Ferreras A, Archer J. Validation of thromboelastography in healthy dairy cows. Journal of Dairy Science (2014) 97(9): 5474-80.

Williams TL, Elliott J and Syme HM. Effect on renal function of restoration of euthyroidism in hyperthyroid cats with iatrogenic hypothyroidism. Journal of Veterinary Internal Medicine (2014) 28(4): 1251-55.

Williams TL, Elliott J and Syme HM. Association between urinary excretion of vascular endothelial growth factor and chronic kidney disease in hyperthyroid cats. Research in Veterinary Science. (2014) 96: 436-441.

Williams TL, Elliott J, Berry J and Syme HM. Investigation of the pathophysiological mechanism for altered calcium homeostasis in hyperthyroid cats. Journal of Small Animal Practice (2013) 54: 367-373.

Williams TL, Elliott J and Syme HM. Renin-angiotensin-aldosterone system activity in hyperthyroid cats with and without concurrent hypertension. Journal of Veterinary Internal Medicine (2013) 27(3): 622-629.